Why do pimples (zits) on the inside of your nostrils hurt so much more than any others?

The tissue inside your nose isn't very thick and has tons of specialized nerve cells right at the surface, which means that when a pore swells with infection (a zit), the skin is pulled tight and the pressure under the already thin tight skin pushes against all those nerves, causing signals to fire and increasing the painful sensation. Plus there just isn't much space in there.